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Pregabalin is a prescription medicine used across the globe for treating neuropathic pain and seizure disorders.
However, it can also lead to dependence. Over time, this may develop into pregabalin addiction, especially if the dose increases or the medicine is used for a long time.
Getting help early can make it easier to manage your pregabalin use and protect your health long-term.
Smarmore Castle is a private rehab clinic set in quiet, rural surroundings around an hour from Dublin.
We specialise in supporting people through addiction, including pregabalin, by supporting safe withdrawal and guiding them towards lasting recovery.
What is pregabalin?
Pregabalin belongs to a class of drugs called gabapentinoids. These work by changing the way nerves transmit signals in the brain and spinal cord, which can help reduce pain, ease anxiety, or prevent certain types of seizures.
Pregabalin is sold under different brand names, and you might recognise it as Lyrica, but it works the same no matter what it’s called.
What is pregabalin used for?
Pregabalin is generally prescribed for:
- Nerve pain
- Epilepsy, usually as an additional treatment alongside other medications
- Generalised anxiety disorder
Some people start taking pregabalin for a medical reason but may begin to rely on it to cope with feelings or physical symptoms.
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Pregabalin side effects
Like any medication, pregabalin can cause side effects. These are usually mild at first but may become more pronounced with higher doses or prolonged use.
Common pregabalin side effects include:
- Dizziness or drowsiness
- Blurred vision
- Dry mouth
- Headaches
- Mood changes
- Digestive problems or upset stomach
- Erectile dysfunction
- Weight gain
- Swelling in the hands or feet
- Problems with memory or concentration
These effects become more likely, and more serious, when pregabalin is combined with other substances, particularly alcohol.
Pregabalin side effects long-term
Using pregabalin for a long time can affect both your body and mind in various ways.
Some people experience persistent fatigue or low mood, and some say they feel emotionally flat.
Others notice trouble with coordination or find their anxiety gets worse between doses. Any unexpected physical changes are worth discussing with a doctor.
More concerning long-term side effects could include changes in blood glucose levels, signs of psychosis, or a higher risk of injury if taken with other depressants such as alcohol or opioids. In rare cases, kidney damage and heart failure have been reported with long-term use of pregabalin.
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Pregabalin withdrawal symptoms
Stopping pregabalin, especially after regular use, can trigger withdrawal symptoms.
These uncomfortable symptoms are one of the reasons that any prescription drug addiction can feel so difficult to break without support.
Common pregabalin withdrawal symptoms include:
- Anxiety or panic
- Sleep problems
- Sweating or flu-like symptoms
- Headaches
- Nausea
- Diarrhoea
- Low mood or irritability
- Depression or suicidal thoughts in some cases
If you stop taking pregabalin suddenly, it also carries a risk of seizures or convulsions. A gradual reduction under medical supervision is safer, easier on your body, and more likely to succeed.
In Ireland, there have been warnings about people using pregabalin for non-medical reasons, which can make dependence and other serious health problems much more likely.
Alcohol and pregabalin
A common question is whether it’s safe to drink alcohol while taking pregabalin. The short answer is no. Alcohol increases the sedative effects of the medication, which can slow your breathing and raise the risk of accidents or injury.
Mixing the two also makes it easier to develop a dependence on one or both substances.
Prescription drug detox and treatment
If pregabalin use has become hard to manage, professional addiction treatment can help.
At Smarmore Castle, we offer medically supervised detox followed by therapy and ongoing support.
Our approach focuses on helping your body adjust safely and understanding the underlying reasons behind your drug use. Treatment is private, personalised, and designed around your specific situation.
Support includes:
- Safe withdrawal planning
- Psychological therapy
- Relapse prevention support
- Family involvement where appropriate
You can also complete our free prescription drug and alcohol addiction assessment online to better understand your situation before getting in touch with us.
Learn more about safe prescription drug detox at Smarmore Castle.
Getting help for pregabalin addiction
If pregabalin is affecting your health, your relationships, or your ability to get through the day, support is available. Addressing the problem early can prevent it from becoming more serious, and recovery is possible with the right help.
Smarmore Castle has been helping people recover from addiction since 1988. If you‘d like to speak with our team confidentially, contact us today to discuss your options.
Call us on +353419865080
Take the first step
Call our team today if you’re worried about pregabalin use. We can explain your options and help you plan a safe path forward. We’ll also answer any questions you may have.
Free Confidential Addiction Assessment
Reaching out for help can feel daunting, our team is here to guide you.
Frequently asked questions
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What is pregabalin vs gabapentin?
Pregabalin and gabapentin are both medicines used for nerve pain, but pregabalin is absorbed faster and can have a stronger effect. Both drugs carry a risk of dependence.
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Does pregabalin cause hair loss?
Pregabalin is not commonly associated with hair loss. While some anticonvulsant drugs can cause alopecia, it’s very rare with gabapentinoids like pregabalin.
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Can you drink alcohol while taking pregabalin?
Drinking alcohol should be avoided by those taking pregabalin. Taking both at the same time can make you very drowsy and slow down your breathing. It can also increase the risk of accidents. These effects are stronger at higher doses and can be dangerous.
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Are pregabalin and Lyrica the same thing?
Yes, they are the same. Lyrica is a brand name, while pregabalin is the active ingredient in the drug. No matter the name, the effects and risks are the same.
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Can I take paracetamol with pregabalin?
Yes, paracetamol and pregabalin work in different ways, so they are generally safe to take together. If you’re taking a combination painkiller such as co-codamol, however, you should check with your doctor. These drugs work differently and can worsen the side effects of pregabalin in some cases.
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How long does pregabalin stay in your system?
Pregabalin usually stays in the body for about one to two days. The exact time can vary depending on the dose, how long someone has been taking it, and how healthy their kidneys are.
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Is pregabalin safe?
Pregabalin, when used properly, should be safe. Taking it in larger doses than prescribed heightens the risks, and the dangers worsen when it’s used for long periods. Mixing it with alcohol or other drugs can also lead to serious problems.