Ketamine addiction: Signs, risks, and treatment

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Victoria McCann BA, MSc
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Dr Ralf Warren MB ChB Bsc.
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The use of ketamine is growing among younger populations in Ireland and across Europe. Whilst there’s a growing awareness about the impact of ketamine, many people begin by taking it socially. Use can be slow, and many people think that because they only use it recreationally, they won’t experience any physical symptoms. When people begin to experience ketamine addiction symptoms, they don’t always connect them with their drug use.

As one person described in recovery, it can be easy to distance yourself from thoughts of addiction. Or you may even think your symptoms are down to another reason, like a different medical condition. For some people, dependence develops more quickly than expected.  Symptoms can affect mental health, physical health, and daily life, and some effects do require longer-term management. Getting support early makes a real difference.

Ketamine addiction is real, and its consequences are too, but treatment in early dependence can make a difference to recovery.

Smarmore Castle has been treating ketamine addiction since 2015, and we have seen increasing numbers of people coming to rehab for treatment for ketamine misuse and addiction. We’re here to support your recovery. If you need to come to rehab, our specialist ketamine detox unit and programme of therapy, relapse prevention, and continuing care is designed to give you the strong foundations. We will provide ongoing support to start your recovery with the right tools in place.

What is ketamine addiction?

Ketamine is a dissociative anaesthetic. It produces feelings of detachment from your body and your surroundings. It was developed for medical use. It remains a licensed anaesthetic and is used in controlled settings to treat certain types of pain and treatment-resistant depression. But outside those settings, its effects make it easy to misuse.

When you take ketamine repeatedly, your brain adjusts to it. Ketamine works by blocking certain receptors in the brain, which disrupts normal communication between nerve cells. Over time, this affects the brain’s reward system, making it harder to feel pleasure without it. Psychological dependence means your mind comes to rely on ketamine. This happens even when your body does not have a physical need for it.

Ketamine addiction does not require daily use. Some people develop a strong compulsion to use it after weeks of occasional use. Frequency matters less than control. If stopping feels harder than you expected, it’s worth speaking to someone.

Why ketamine use is increasing

Ketamine is no longer a niche concern. Between 2018 and 2023, the number of people entering treatment for ketamine misuse across Europe rose more than fourfold. This went from around 300 to 1,380. That figure comes from the European Union Drugs Agency’s European Drug Report 2025

In Ireland, the scale of the problem is becoming clearer. Seizures of ketamine by Revenue increased from 7.86 kg in 2022 to 41.2 kg in 2023, a sharp rise that reflects both greater supply and greater use. 

Ketamine is particularly prevalent in nightlife communities and among younger people, though its use extends well beyond those groups.

The rise in ketamine use is happening alongside growing awareness of its risks. If you are reading this, you may already be questioning your own relationship with it or be concerned about someone you care about.

Signs and symptoms of ketamine addiction

Recognising the signs of ketamine addiction in yourself is not always straightforward. The changes can be gradual, and it’s easy to explain them away.

Behavioural signs

You might notice that you are spending more time planning to use ketamine or recovering from using it. Common signs are secrecy around use, spending more money than you intended, withdrawing from people and activities you used to value. 

You may find yourself in situations you would previously have avoided. Or you may be mixing ketamine with other substances to intensify or extend the effect.

Psychological symptoms

Ketamine affects mood significantly. Mood swings and low mood are common in the days after using. Some people describe a flattening of feeling that makes ordinary life harder to engage with. Memory and concentration are also affected by regular use.

Physical symptoms

The physical signs of ketamine misuse are distinct. Bladder and urinary problems, including pain, frequent urination, and difficulty emptying the bladder, are among the most serious. They are closely associated with regular ketamine use. 

You may also notice ketamine side effects such as slurred speech, slowed reactions, or periods of appearing sedated or unresponsive during use. Severe abdominal cramping, sometimes called ‘K cramps’, is another physical sign of prolonged misuse.

The risks of ketamine misuse

Ketamine carries risks even when it’s not used every day. In the short term, it can cause respiratory depression, a raised heart rate, and raised blood pressure. It can also trigger intense dissociative episodes. These are sometimes called a ‘K-hole’ (a state where you lose awareness of your surroundings and are unable to move or respond).

With sustained use, the risks compound. Memory loss and cognitive difficulties become more pronounced. Psychological symptoms can begin to resemble psychosis. And the body develops tolerance, meaning you need more ketamine to achieve the same effect, a pattern that accelerates physical harm.

Using ketamine alongside other substances, particularly alcohol or stimulants, increases the risk of serious harm. The combined effect on the heart, breathing, and consciousness can be unpredictable and difficult to reverse.

Heavy ketamine use can take a significant toll on mental health over time. If you are struggling, please speak to someone today. You can contact our team directly.

Many people who misuse ketamine also live with depression, anxiety, or another mental health condition. Sometimes, ketamine use begins as a way of managing those feelings. Over time, it tends to make them worse. If this sounds familiar, treatment at Smarmore Castle addresses both your mental health and your ketamine use together.

Ketamine bladder: what you need to know

Ketamine bladder syndrome is one of the most serious consequences of sustained ketamine misuse, and one of the least well understood. The condition causes the bladder to shrink and stiffen. This can lead to severe pain, the urgent and frequent need to urinate, and in some cases, the inability to hold any urine at all.

The Health Research Board has recommended that Irish physicians be aware of the signs of long-term ketamine use. This is particularly important in young people presenting with cognitive or bladder problems. 

The only way to stop ketamine bladder syndrome from getting worse is to stop using ketamine.

Read our full explanation of ketamine bladder syndrome and its treatment.

Ketamine withdrawal and detox

If you have been using ketamine regularly, stopping is unlikely to feel straightforward. Ketamine withdrawal differs from coming off alcohol or opioids. There are no severe physical symptoms, but the psychological pull can be strong. In the days after stopping, cravings can be powerful, and low mood, anxiety, and broken sleep are common.

For many people, the safest way to stop is with medical support. A supervised detox means you are not managing withdrawal alone. It can also mean that any complications, physical or psychological, can be responded to quickly. At Smarmore Castle, detox takes place in a structured clinical environment, with 24-hour support from our medical team.

If you are thinking about stopping ketamine, we would encourage you to speak to someone before you do. You can contact our admissions team at any time. 

Ketamine addiction treatment at Smarmore Castle

We offer residential ketamine addiction treatment at Smarmore Castle, set in County Louth. Treatment is structured, evidence-based, and built around your individual needs, because no two people arrive at this point the same way.

Medical and clinical assessment

Before treatment begins, you will have a full assessment covering your physical health, mental health, and life circumstances with our clinical team. This looks at your physical and mental health, your history with ketamine, and the wider circumstances of your life. It shapes everything that follows.

Detox and stabilisation

If you need a medically supervised detox, this takes place in the first stage of your stay. Our medical team monitors you throughout, manages any withdrawal symptoms, and ensures you are physically stable before the therapeutic work begins.

Therapy and psychological support

The core of treatment at Smarmore Castle is psychological. You will work with our clinical team in individual therapy and group sessions. Cognitive Behavioural Therapy (CBT), trauma-informed care, and 12 Step work each address a different part of the same problem.

Continuing care

Treatment at Smarmore Castle does not stop at discharge. Before you leave, we’ll work with you to build a continuing care plan. This might include ongoing therapy, peer support through groups like Narcotics Anonymous (NA), and regular contact with our team. Recovery does not stop at discharge, and neither does our support.

Can you recover from ketamine addiction?

Recovery from ketamine addiction is possible, but it’s worth being honest about what that involves.

The first weeks after treatment are often the hardest. Others find that stress or significant life events test their resolve further down the line. Relapse is part of many people’s recovery journeys, and it does not mean treatment has failed.

What matters is having support in place before you need it. The people who do best in long-term recovery tend to have built a network of clinical support, peer support, and people who understand what they are going through. At Smarmore Castle, helping you build that network is part of what we do.

If you are a family member reading this, recovery is also possible for the people you love. It’s often a longer road than anyone expects, and it asks a great deal of everyone involved. Our team can speak with you, too, whether or not the person you are concerned about is ready to seek help yet.

When to seek help

If you are questioning your ketamine use, that question is worth taking seriously. You do not need to have lost everything, hit a crisis point, or be using every day to deserve support.

Some signs that it may be time to speak to someone: 

  • You have tried to cut down and found it harder than expected 
  • Your use is affecting your health, your work, or your relationships 
  • You are using ketamine to manage your mood or cope with difficult feelings, or someone who cares about you has raised a concern.

If any of those feel familiar, we are here. You can speak to our admissions team about ketamine rehab. There’s no obligation, no pressure, and no requirement to have made any decisions yet.

Speak to our team

Frequently Asked Questions

  • Is ketamine addictive?

    Yes. Ketamine produces strong psychological dependence, and some people also develop signs of physical dependence with regular use. Addiction can develop even without daily use; the key factor is whether you feel in control of your use.

  • What are the long-term effects of ketamine?

    Memory loss and difficulty concentrating are common when people use ketamine long-term. One of the most serious physical risks is damage to your bladder. In some cases,  mental health symptoms can appear much like psychosis.

  • What is ketamine bladder?

    Ketamine bladder syndrome is a condition caused by sustained ketamine misuse. It causes the bladder to shrink and stiffen, leading to severe pain, frequent urination, and in serious cases, permanent damage. The only way to stop ketamine bladder syndrome from getting worse is to stop using ketamine.

  • Can you stop ketamine on your own?

    Some people do stop without professional support. But withdrawal can take its toll on your mental health. The risk of returning to use is high without structured support in place. If you have been using it regularly or heavily, getting help and advice from your GP is something we would strongly recommend.

  • How is ketamine addiction treated?

    Treatment typically involves a medically supervised detox if needed, followed by a structured programme of psychological therapies. At Smarmore Castle, this includes Cognitive Behavioural Therapy (CBT), trauma-informed approaches, and 12 Step work, alongside continuing care planning for life after treatment.

  • Can people recover from ketamine addiction?

    People do recover from drug addiction. For ketamine addiction, recovery is not always a smooth process, but with support, it’s achievable. This is especially when it is recognised and stopped early.


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